This is disappointing for those who believe that taking large doses of B vitamins will help to reduce their risk of chronic disease.
So what does this mean for you? Dietary supplements are certainly valuable for preventing vitamin deficiencies, however taking larger doses isn't going to undo the damage done by eating a poor diet (or other unhealthy risk factors).
Rather than focusing on dietary supplements, you should be thinking about your diet instead. Are you getting at least five or more servings of fruits and vegetables? Do you eat whole grains? Do you avoid unhealthy fats and choose foods cooked with healthy methods?
You'll do more for your health by eating a balanced diet than you ever will by popping vitamin pills.

